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This dilution of the grape must was performed because the pure grape juice consumes oxygen so fast that it is nearly impossible to monitor correctly the oxygen concentration of all the samples

Pang SS, Nguyen STS, Perry AJ, Day CJ, Panjikar S, Tiralongo J, Whisstock JC, Kwok T (2014) The three-dimensional structure of the extracellular adhesion domain of the sialic acid-binding adhesin SabA from Helicobacter pylori

However, oxidants produced by ROS, including 4-HNE and MDA, change the structure of proteins, thereby inducing apoptosis and regulating the release of inflammatory cytokines (5)

10.1016/s1050-1738(02)00175-5 20

Low BPA concentrations can activate these pathways 106 and thyroid mediated nongenomic signaling involves MAPK/ERK and Akt pathways 105